Leeds Institute of Genetics, Health and Therapeutics (LIGHT)
Mark S Gilthorpe
Professor of Statistical Epidemiology and Institute Director
Biostatistics
Qualifications: BSc, PhD, FHEA
Email: M.S.Gilthorpe@leeds.ac.uk
Telephone: 0113 343 1913
Research Area
Statistical Epidemiology in Lifecourse Epidemiology
Details
In biomedical observational research, evidence of underlying association between an exposure and subsequent disease is difficult to demonstrate unequivocally. Evidence of causation may only be inferred, yet there are many real-life situations for which we seek an understanding that cannot be subjected to experimentation. Epidemiology, the methodological foundation of observational research, provides structure to the conduct of biomedical research through appropriate study design, conduct, and statistical analysis. However, many study designs experience real analytical challenges and overcoming these is an ongoing mission for applied methodological researchers such as myself. In my main area of interest - lifecourse epidemiology - one studies adverse events in later life in relation to exposures that may have occurred throughout the lifecourse, possibly before birth and during pregnancy. Moreover, it is the accumulative compounding experiences of many exposures throughout life from conception, birth, and early childhood, through adolescence, early adulthood and older age, that one has to disentangle in the search for putative factors that affect health and well-being and which may lead to disease and morbidity or ultimately death. My research seeks new analytical strategies for these types of observational problems within epidemiology. I therefore focus on the development of robust statistical methodology and the appropriate application of statistical modelling to examine observational (often cohort) data, to assess if and how potential experiences throughout the lifecourse might lead to adverse health outcomes later in life. I examine human growth and seek to establish appropriate analytical strategies to inform research questions in relation to a variety of health outcomes (cardiovascular disease, cancer, childhood obesity, anxiety, depression, to name but a few).
Recent Projects
Methods for modelling repeated measures in a lifecourse framework Medical Research Council, UK Apr 11 - Mar 14 £415,439 (joint with Bristol University; £74,889 to Leeds). Answering questions about the relative importance of aspects and timing of growth, behaviour and health status for longer-term outcomes requires longitudinal data, but there are many challenges analysing these data by standard regression models. This project focuses on developing more robust methods for the analysis of such data, addressing issues around detecting and modelling autocorrelation, lack of constant variance within growth trajectories, and the selection of a best-fitting parameterisation of growth curves. We use our new methods to answer scientifically important questions pertaining to ALSPAC and data from other longitudinal studies available to co-applicants.
Leukaemia and other cancers in teenagers and young adults in England: an aetiological analysis applying new statistical approaches Children with Leukaemia, Apr 09 - Mar 12 £120,351. This project addresses the paucity of information on the causes of teenage and young adult leukaemia, lymphoma and central nervous system tumours by carrying out a programme of aetiological research focusing on infections. The work exploits the national cancer dataset available from the North West Cancer Intelligence Service for 7,000 individuals aged 15-24 years, diagnosed 1996-2006. Structural equation modelling and latent variable analyses will be used to investigate the timing of infection using a validated surrogate measure, providing new insights into the causes of cancer diagnosed in teenagers and young adults. This study will test the hypothesis of an infectious aetiology.
EnviroGenoMarkers: Genomics biomarkers of environmental health European Framework 7, Brussels Mar 09 – Feb 12 (joint with 10 partners; €204,000 to Leeds). This proposal is the first large-scale application of the whole range of ‘omics’ technologies in a population study aiming at: (a) the discovery and validation of novel biomarkers predictive of increased risks of chronic diseases in which the environment may play an important role (breast cancer, non-Hodgkin’s lymphoma, allergy, neurological and immune diseases, thyroid disruption); (b) the exploration of the association of such risk biomarkers with environmental exposures, including high-priority pollutants (carcinogens and immunetoxicants such as PCBs and PAHs, neurotoxicants such as cadmium, lead and ambient air pollution) and emerging exposures (such as phthalates and brominated flame retardants), many of which are also endocrine disruptors; and (c) the discovery and validation of biomarkers of exposure to the above and other high-priority environmental exposures (e.g. water disinfection by products). Leeds is the data warehouse and provides statistical bioinformatics expertise in the discovery and subsequent analyses stages.
Improved statistical modelling for observational research: understanding and addressing the problems associated with collinearity Medical Research Council, UK Oct 08 - Sep 12 £89,000 Statistical models with correlated covariates suffer collinearity. It is essential to distinguish between the positive (confounder adjusted) and adverse (biased) effects of collinearity. This project will distinguish between positive and negative impacts of collinearity and generate algorithms to assist systematically in the model building process to provide minimally biased estimates observational studies.
Publications
Recent
Kubzansky LD; Gilthorpe MS; Goodman E (2012) A Prospective Study of Psychological Distress and Weight Status in Adolescents/Young Adults. ANNALS OF BEHAVIORAL MEDICINE, 43 , pp. 219-228.
Morris E; Haward RA; Gilthorpe MS; Craigs C; Forman D The impact of the Calman-Hine report on the processes and outcomes of care for Yorkshire’s breast cancer patients.. Annals of Oncology, .
Selected
Tu Y; Chien K; Burley V; Gilthorpe MS (2011) Unravelling the effects of age, period and cohort on metabolic syndrome components in a Taiwanese population using partial least squares regression. BMC MEDICAL RESEARCH METHODOLOGY, 11 .
Tu Y; Smith GD; Gilthorpe MS (2011) A New Approach to Age-Period-Cohort Analysis Using Partial Least Squares Regression: The Trend in Blood Pressure in the Glasgow Alumni Cohort. PLOS ONE, 6 .
All
Kubzansky LD; Gilthorpe MS; Goodman E (2012) A Prospective Study of Psychological Distress and Weight Status in Adolescents/Young Adults. ANNALS OF BEHAVIORAL MEDICINE, 43 , pp. 219-228.
McKeown L; Moss NK; Turner P; Li J; Heath N; Burke D; O'Regan D; Gilthorpe MS; Porter KE; Beech DJ (2012) Platelet-derived growth factor maintains stored calcium through a nonclustering orai1 mechanism but evokes clustering if the endoplasmic reticulum is stressed by store depletion. Circulation Research, .
Tu Y; Gilthorpe MS (2012) Key statistical and analytical issues for evaluating treatment effects in periodontal research. PERIODONTOLOGY 2000, 59 , pp. 75-88.
Woolston A; Tu Y; Baxter PD; Gilthorpe MS (2012) A comparison of different approaches to unravel the latent structure within metabolic syndrome. PLoS ONE, 7 (4).
Downing A; Gilthorpe MS; Dodwell D; Lawrence G; Forman D (2011) Waiting Times for Radiotherapy after Breast-conserving Surgery and the Association with Survival: A Path Analysis. CLINICAL ONCOLOGY, 23 , pp. 442-448.
Tu Y; Chien K; Burley V; Gilthorpe MS (2011) Unravelling the effects of age, period and cohort on metabolic syndrome components in a Taiwanese population using partial least squares regression. BMC MEDICAL RESEARCH METHODOLOGY, 11 .
Tu Y; Smith GD; Gilthorpe MS (2011) A New Approach to Age-Period-Cohort Analysis Using Partial Least Squares Regression: The Trend in Blood Pressure in the Glasgow Alumni Cohort. PLOS ONE, 6 .
Gilthorpe MS; Harrison WJ; Downing A; Forman D; West RM (2011) Multilevel latent class casemix modelling: a novel approach to accommodate patient casemix. BMC HEALTH SERVICES RESEARCH, 11 .
Tu Y; Summers LKM; Burley V; Chien K; Law GR; Fleming T; Gilthorpe MS (2011) Trends in the association between blood pressure and obesity in a Taiwanese population between 1996 and 2006. JOURNAL OF HUMAN HYPERTENSION, 25 , pp. 88-97.
Kubzansky LD; Gilthorpe MS; Goodman E (2011) A Prospective Study of Psychological Distress and Weight Status in Adolescents/Young Adults. Annals of Behavioral Medicine, , pp. 1-10.
Downing A; Harrison WJ; West RM; Forman D; Gilthorpe MS (2010) Latent class modelling of the association between socioeconomic background and breast cancer survival status at 5 years incorporating stage of disease. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 64 , pp. 772-776.
Tu Y; Woolston A; Baxter PD; Gilthorpe MS (2010) Assessing the Impact of Body Size in Childhood and Adolescence on Blood Pressure An Application of Partial Least Squares Regression. EPIDEMIOLOGY, 21 , pp. 440-448.
Zagari RM; Law GR; Fuccio L; Cennamo V; Gilthorpe MS; Forman D; Bazzoli F (2010) Epidemiology of Functional Dyspepsia and Subgroups in the Italian General Population: An Endoscopic Study. GASTROENTEROLOGY, 138 , pp. 1302-1311.
Tu Y; Law GR; Ellison GTH; Gilthorpe MS (2010) Ratio index variables or ANCOVA? Fisher's cats revisited. PHARMACEUTICAL STATISTICS, 9 , pp. 77-83.
Gilthorpe MS; Frydenberg M; Cheng Y; Baelum V (2009) Modelling count data with excessive zeros: The need for class prediction in zero-inflated models and the issue of data generation in choosing between zero-inflated and generic mixture models for dental caries data. STATISTICS IN MEDICINE, 28 , pp. 3539-3553.
Manda SOM; Feltbower RG; Gilthorpe MS (2009) Investigating spatio-temporal similarities in the epidemiology of childhood leukaemia and diabetes. EUROPEAN JOURNAL OF EPIDEMIOLOGY, 24 , pp. 743-752.
Tu Y; Gilthorpe MS; D' Aiuto F; Woolston A; Clerehugh V (2009) Partial least squares path modelling for relations between baseline factors and treatment outcomes in periodontal regeneration. JOURNAL OF CLINICAL PERIODONTOLOGY, 36 , pp. 984-995.
Tu Y; D'Aiuto F; Baelum V; Gilthorpe MS (2009) An introduction to latent growth curve modelling for longitudinal continuous data in dental research. EUROPEAN JOURNAL OF ORAL SCIENCES, 117 , pp. 343-350.
Head RF; Gilthorpe MS; Ellison GTH (2009) Cholesterol levels in later life amongst uk Channel islanders exposed to the 1940-45 German occupation as children, adolescents and young adults. Nutrition and Health, 20 (2), pp. 91-105.
Head RF; Gilthorpe MS; Byrom A; Ellison GTH (2008) Cardiovascular disease in a cohort exposed to the 1940-45 Channel Islands occupation. BMC PUBLIC HEALTH, 8 .
Taylor JC; Law GR; Boyle PJ; Feng Z; Gilthorpe MS; Parslow RC; Rudge G; Feltbower RG (2008) Does population mixing measure infectious exposure in children at the community level?. EUROPEAN JOURNAL OF EPIDEMIOLOGY, 23 , pp. 593-600.
Tu Y; Baelum V; Gilthorpe MS (2008) A structural equation modelling approach to the analysis of change. EUROPEAN JOURNAL OF ORAL SCIENCES, 116 , pp. 291-296.
Downing A; Forman D; Gilthorpe MS; Edwards KL; Manda SOM (2008) Joint disease mapping using six cancers in the Yorkshire region of England. INTERNATIONAL JOURNAL OF HEALTH GEOGRAPHICS, 7 .
Tu YK; Galobardes B; Davey Smith G; McCarron P; Jeffreys M; Gilthorpe MS (2008) Tooth loss and mortality patterns.. Heart, 94 (3), pp. 368.
Tu Y; Galobardes B; Smith GD; McCarron P; Jeffreys M; Gilthorpe MS (2008) Tooth loss and mortality patterns - Reply. HEART, 94 , pp. 368-368.
Morris E; Haward RA; Gilthorpe MS; Craigs C; Forman D (2008) The impact of the Calman-Hine report on the processes and outcomes of care for Yorkshire's breast cancer patients. ANNALS OF ONCOLOGY, 19 , pp. 284-291.
Morris E; Haward RA; Gilthorpe MS; Craigs C; Forman D (2008) The impact of the Calman-Hine report on the processes and outcomes of care for Yorkshire's breast cancer patients. Annals of Oncology, 19 (2), pp. 284-291.
Downing A; Rudge G; Cheng Y; Tu Y; Keen J; Gilthorpe MS (2007) Do the UK government's new Quality and Outcomes Framework (QOF) scores adequately measure primary care performance? A cross-sectional survey of routine healthcare data. BMC HEALTH SERVICES RESEARCH, 7 .
West RM; Harris K; Gilthorpe MS; Tolman C; Will EJ (2007) Functional data analysis applied to a randomized controlled clinical trial in hemodialysis patients describes the variability of patient responses in the control of renal anemia. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 18 , pp. 2371-2376.
Tu Y; Gilthorpe MS (2007) Revisiting the relation between change and initial value: A review and evaluation. STATISTICS IN MEDICINE, 26 , pp. 3205-3206.
Tu Y; Gilthorpe MS (2007) Revisiting the relation between change and initial value: A review and evaluation - Author's reply. STATISTICS IN MEDICINE, 26 , pp. 3206-3208.
Mensah FK; Gilthorpe MS; Davies CE; Keen LJ; Adamson PJ; Roman E; Morgan GJ; Bidwell JL; Law GR (2007) Haplotype uncertainty in association studies. GENETIC EPIDEMIOLOGY, 31 , pp. 348-357.
Manda SOM; Walls RE; Gilthorpe MS (2007) A full Bayesian hierarchical mixture model for the variance of gene differential expression. BMC BIOINFORMATICS, 8 .
Needleman I; Suvan J; Gilthorpe MS; Tucker R; St George G; Giannobile W; Tonetti M; Jarvis M (2007) A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers. JOURNAL OF CLINICAL PERIODONTOLOGY, 34 , pp. 325-333.
Downing A; Prakash K; Gilthorpe MS; Mikeljevic JS; Forman D (2007) Socioeconomic background in relation to stage at diagnosis, treatment and survival in women with breast cancer. BRITISH JOURNAL OF CANCER, 96 , pp. 836-840.
Tu Y; Gilthorpe MS (2007) Unexplained residuals models are not solutions to statistical modeling of the fetal origins hypothesis. JOURNAL OF CLINICAL EPIDEMIOLOGY, 60 , pp. 318-319.
Walls RE; Barber S; Kent JT; Gilthorpe MS (2007) An adaptive empirical Bayesian thresholding procedure for analysing microarray experiments with replication. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 56 , pp. 271-291.
Tu Y; Gilthorpe MS (2007) Authors' reply [2]. Statistics in Medicine, 26 (16), pp. 3206-3208.
Greenwood DC; Ransley JK; Gilthorpe MS; Cade JE (2006) Use of itemized till receipts to adjust for correlated dietary measurement error. AMERICAN JOURNAL OF EPIDEMIOLOGY, 164 , pp. 1012-1018.
Tu Y; Gilthorpe MS; Ellison GTH (2006) What is the effect of adjusting for more than one measure of current body size on the relation between birthweight and blood pressure?. JOURNAL OF HUMAN HYPERTENSION, 20 , pp. 646-657.
Tu Y; Sterne JAC; Gilthorpe MS (2006) Growth trajectory and regression to the mean in the foetal origins hypothesis. EARLY HUMAN DEVELOPMENT, 82 , pp. 504-504.
Greenwood DC; Gilthorpe MS; Cade JE (2006) The impact of imprecisely measured covariates on estimating gene-environment interactions. BMC Medical Research Methodology, 6 .
Tu Y; Ellison GTH; Gilthorpe MS (2006) Growth, current size and the role of the 'reversal paradox' in the foetal origins of adult disease: An illustration using vector geometry. Epidemiologic Perspectives and Innovations, 3 .
Blance A; Tu YK; Gilthorpe MS (2005) A multilevel modelling solution to mathematical coupling. STATISTICAL METHODS IN MEDICAL RESEARCH, 14 , pp. 553-565.
Manda SOM; Gilthorpe MS; Tu YK; Blance A; Mayhew MT (2005) A Bayesian analysis of amalgam restorations in the Royal Air Force using the counting process approach with nested frailty effects. STATISTICAL METHODS IN MEDICAL RESEARCH, 14 , pp. 567-578.
Tu YK; Kellett M; Clerehugh V; Gilthorpe MS (2005) Problems of correlations between explanatory variables in multiple regression analyses in the dental literature. BRITISH DENTAL JOURNAL, 199 , pp. 457-461.
Tu YK; Ellison GTH; West R; Gilthorpe MS (2005) Re: "Why evidence for the fetal origins of adult disease might be a statistical artifact: The 'reversal paradox' for the relation between birth weight and blood pressure in later life" - Authors reply. AMERICAN JOURNAL OF EPIDEMIOLOGY, 162 , pp. 395-395.
Tu YK; Gilthorpe M (2005) Re: Relative connective tissue graft size affects root coverage treatment outcome in the envelope procedure. Yotnuengnit P, Promsudthl A, Teparat T, Laohapand P, Yuwaprecha W (2004;75 : 886-892).. JOURNAL OF PERIODONTOLOGY, 76 , pp. 1403-1403.
Tu YK; Baelum V; Gilthorpe MS (2005) The problem of analysing the relationship between change and initial value in oral health research. EUROPEAN JOURNAL OF ORAL SCIENCES, 113 , pp. 271-278.
Tu YK; Ellison GTH; West RM; Gilthorpe MS (2005) Re: "Why evidence for the fetal origins of adult disease might be a statistical artifact: The 'reversal paradox' for the relation between birth weight and blood pressure in later life" - Reply. AMERICAN JOURNAL OF EPIDEMIOLOGY, 162 , pp. 293-293.
Tu YK; Baelum V; Gilthorpe MS (2005) The relationship between baseline value and its change: problems in categorization and the proposal of a new method. EUROPEAN JOURNAL OF ORAL SCIENCES, 113 , pp. 279-288.
Tu YK; Gilthorpe M (2005) Re: Relative connective tissue graft size affects root coverage treatment outcome in the envelope procedure.. J Periodontol, 76 (8), pp. 1403-1405.
Ahmed TR; Mordan NJ; Gilthorpe MS; Gillam DG (2005) In vitro quantification of changes in human dentine tubule parameters using SEM and digital analysis. JOURNAL OF ORAL REHABILITATION, 32 , pp. 589-597.
Feltbower RG; Manda SOM; Gilthorpe MS; Greaves MF; Parslow RC; Kinsey SE; Bodansky HJ; McKinney PA (2005) Detecting small-area similarities in the epidemiology of childhood acute lymphoblastic leukemia and diabetes mellitus, type 1: A Bayesian approach. AMERICAN JOURNAL OF EPIDEMIOLOGY, 161 , pp. 1168-1180.
Tu YK; Gilthorpe MS (2005) Commentary: Is tooth loss good or bad for general health?. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 34 , pp. 475-476.
Tu YK; Blance A; Clerehugh V; Gilthorpe MS (2005) Statistical power for analyses of changes in randomized controlled trials. JOURNAL OF DENTAL RESEARCH, 84 , pp. 283-287.
Ciantar M; Gilthorpe MS; Hurel SJ; Hewman HH; Wilson M; Spratt DA (2005) Capnocytophaga spp. in periodontitis patients manifesting diabetes mellitus. JOURNAL OF PERIODONTOLOGY, 76 , pp. 194-203.
Tu YK; Ellison GTH; West R; Gilthorpe MS (2005) Invited commentary: Barker meets Simpson - TU et al. Respond to "Barker meets Simpson". AMERICAN JOURNAL OF EPIDEMIOLOGY, 161 , pp. 36-37.
Tu YK; West R; Ellison GTH; Gilthorpe MS (2005) Why evidence for the fetal origins of adult disease might be a statistical artifact: The "reversal paradox" for the relation between birth weight and blood pressure in later life. AMERICAN JOURNAL OF EPIDEMIOLOGY, 161 , pp. 27-32.
Tu YK; West RM; Ellison GT; Gilthorpe MS (2005) Tu et al. respond to "Barker meets Simpson". American Journal of Epidemiology, 161 (1), pp. 36-37.
Cole TJ; Tu Y; Ellison GTH; West R; Gilthorpe MS (2005) Re: "Why evidence for the fetal origins of adult disease might be a statistical artifact: The 'reversal paradox' for the relation between birth weight and blood pressure in later life" [4]. American Journal of Epidemiology, 162 (4), pp. 394-395.
Tu Y; Ellison GTH; West RM; Gilthorpe MS (2005) TU et al. reply [2]. American Journal of Epidemiology, 162 (3), pp. 293-293.
Weinberg CR; Tu Y; Ellison GTH; West R; Gilthorpe MS (2005) Invited commentary: Barker meets Simpson. American Journal of Epidemiology, 161 (1), pp. 33-37.
Gilthorpe MS; Tu YK (2004) Mathematical coupling: a multilevel approach. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 33 , pp. 1399-1400.
Gilthorpe MS; Tu YK; Gunnell D (2004) A coda: oversimplification, implicit assumptions, and measurement error. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 33 , pp. 1402-1403.
Tu YK; Clerehugh V; Gilthorpe MS (2004) Collinearity in linear regression is a serious problem in oral health research. EUROPEAN JOURNAL OF ORAL SCIENCES, 112 , pp. 389-397.
Tu YK; Maddick IH; Griffiths GS; Gilthorpe MS (2004) Mathematical coupling can undermine the statistical assessment of clinical research: illustration from the treatment of guided tissue regeneration (vol, 32, pg 133, 2004). JOURNAL OF DENTISTRY, 32 , pp. 339-340.
Tu YK; Maddick IH; Griffiths GS; Gilthorpe MS (2004) Mathematical coupling can undermine the statistical assessment of clinical research: illustration from the treatment of guided tissue regeneration. JOURNAL OF DENTISTRY, 32 , pp. 133-142.
Tu YK; Clerehugh V; Gilthorpe MS (2004) Ratio variables in regression analysis can give rise to spurious results: illustration from two studies in periodontology. JOURNAL OF DENTISTRY, 32 , pp. 143-151.
El-Sheikh AM; Hobkirk JA; Howell PGT; Gilthorpe MS (2004) Passive tactile sensibility in edentulous subjects treated with dental implants: A pilot study. JOURNAL OF PROSTHETIC DENTISTRY, 91 , pp. 26-32.
Tu YK; Gilthorpe MS; Griffiths GS; Maddick IH; Eaton KA; Johnson NW (2004) The application of multilevel modeling in the analysis of longitudinal periodontal data - Part I: Absolute levels of disease. JOURNAL OF PERIODONTOLOGY, 75 , pp. 127-136.
Tu YK; Gilthorpe MS; Griffiths GS; Maddick IH; Eaton KA; Johnson NW (2004) The application of multilevel modeling in the analysis of longitudinal periodontal data - Part II: Changes in disease levels over time. JOURNAL OF PERIODONTOLOGY, 75 , pp. 137-145.
Tu Y; Maddick IH; Griffiths GS; Gilthorpe MS (2004) Erratum: Mathematical coupling can undermine the statistical assessment of clinical research: Illustration from the treatment of guided tissue regeneration (Journal of Dentistry (2004) 32 (133-142) DOI: 10.1016/j.jdent. 2003.10.001). Journal of Dentistry, 32 (4), pp. 339-340.
El-Sheikh AM; Hobkirk JA; Howell PGT; Gilthorpe MS (2004) Passive tactile sensibility in edentulous subjects treated with dental implants: A pilot study. Journal of Prosthetic Dentistry, 91 (1), pp. 26-32.
Atan S; Ashley P; Gilthorpe MS; Scheer B; Mason C; Roberts G (2004) Morbidity following dental treatment of children under intubation general anaesthesia in a day-stay unit. International Journal of Paediatric Dentistry, 14 (1), pp. 9-16.
Gilthorpe MS; Blance A; Tugnait A; Clerehugh V (2003) The importance of tooth anatomy in choosing appropriate analytical strategies for hierarchical periodontal research data.. JOURNAL OF DENTAL RESEARCH, 82 , pp. B363-B363.
Blance A; Gilthorpe MS; Tu Y; Clerehugh V (2003) A multilevel modeling solution to mathematical coupling in the analysis of change with respect to baseline within periodontal research.. JOURNAL OF DENTAL RESEARCH, 82 , pp. B286-B286.
Clerehugh V; Tu Y; Gilthorpe MS (2003) Statistical problems in periodontal research.. JOURNAL OF DENTAL RESEARCH, 82 , pp. B285-B285.
Gilthorpe MS; Zamzuri AT; Griffiths GS; Maddick IH; Eaton KA; Johnson NW (2003) Unification of the "burst" and "linear" theories of periodontal disease progression: A multilevel manifestation of the same phenomenon. JOURNAL OF DENTAL RESEARCH, 82 , pp. 200-205.
Alkhatib MN; Gilthorpe MS; McGrath C (2002) Disparities in self reported oral health problems among a young Syrian adult population. INTERNATIONAL DENTAL JOURNAL, 52 , pp. 449-452.
Tu YK; Gilthorpe MS; Griffiths GS (2002) Is reduction of pocket probing depth correlated with the baseline value or is it "mathematical coupling"?. JOURNAL OF DENTAL RESEARCH, 81 , pp. 722-726.
Pike R; Lucas V; Stapleton P; Gilthorpe MS; Roberts G; Rowbury R; Richards H; Mullany P; Wilson M (2002) Prevalence and antibiotic resistance profile of mercury-resistant oral bacteria from children with and without mercury amalgam fillings. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 49 , pp. 777-783.
Gilthorpe MS; Mayhew MT; Bulman JS (2002) Multilevel survival analysis of amalgam restorations amongst RAF personnel. Community Dental Health, 19 (1), pp. 3-11.
Cunningham SJ; Gilthorpe MS; Hunt NP (2001) Are pre-treatment psychological characteristics influenced by pre-surgical orthodontics?. EUROPEAN JOURNAL OF ORTHODONTICS, 23 , pp. 751-758.
Griffiths GS; Duffy S; Eaton KA; Gilthorpe MS; Johnson NW (2001) Prevalence and extent of lifetime cumulative attachment loss (LCAL) at different thresholds and associations with clinical variables: changes in a population of young male military recruits over 3 years. JOURNAL OF CLINICAL PERIODONTOLOGY, 28 , pp. 961-969.
Rahbaran S; Gilthorpe MS; Harrison SD; Gulabivala K (2001) Comparison of clinical outcome of periapical surgery in endodontic and oral surgery units of a teaching dental hospital: A retrospective study. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 91 , pp. 700-709.
Gilthorpe MS; Griffiths GS; Maddick IH; Zamzuri AT (2001) An application of multilevel modelling to longitudinal periodontal research data. COMMUNITY DENTAL HEALTH, 18 , pp. 79-86.
Ahmed B; Gilthorpe MS; Bedi R (2001) Agreement between normative and perceived orthodontic need amongst deprived multiethnic school children in London.. Clin Orthod Res, 4 (2), pp. 65-71.
Hodges SJ; Gilthorpe MS; Hunt NP (2001) The effect of micro-etching on the retention of orthodontic molar bands: a clinical trial. EUROPEAN JOURNAL OF ORTHODONTICS, 23 , pp. 91-97.
Eaton KA; Duffy S; Griffiths GS; Gilthorpe MS; Johnson NW (2001) The influence of partial and full-mouth recordings on estimates of prevalence and extent of lifetime cumulative attachment loss: A study in a population of young male military recruits. JOURNAL OF PERIODONTOLOGY, 72 , pp. 140-145.
Lewsey JD; Gilthorpe MS; Gulabivala K (2001) An introduction to meta-analysis within the framework of multilevel modelling using the probability of success of root canal treatment as an illustration. Community Dental Health, 18 (3), pp. 131-137.
Gilthorpe MS; Griffiths GS; Maddick IH; Zamzuri AT (2001) The application of multilevel models to longitudinal dental research data. Community Dental Health, 18 , pp. 79-86.
Gilthorpe MS; Cunningham SJ (2000) The application of multilevel, multivariate modelling to orthodontic research data. COMMUNITY DENTAL HEALTH, 17 , pp. 236-242.
Gilthorpe MS; Griffiths GS; Maddick IH; Zamzuri AT (2000) The application of multilevel modelling to periodontal research data. COMMUNITY DENTAL HEALTH, 17 , pp. 227-235.
Lewsey JD; Gilthorpe MS; Bulman JS; Bedi R (2000) Is modelling dental caries a 'normal' thing to do?. COMMUNITY DENTAL HEALTH, 17 , pp. 212-217.
Gilthorpe MS; Maddick IH; Petrie A (2000) Introduction to Bayesian modelling in dental research. COMMUNITY DENTAL HEALTH, 17 , pp. 218-221.
Maddick IH; Gilthorpe MS (2000) Dentists are dreadful?. COMMUNITY DENTAL HEALTH, 17 , pp. 205-207.
Gilthorpe MS; Maddick IH; Petrie A (2000) Introduction to multilevel modelling in dental research. COMMUNITY DENTAL HEALTH, 17 , pp. 222-226.
Bedi R; Gilthorpe MS (2000) Ethnic and gender variations in university applicants to United Kingdom medical and dental schools. BRITISH DENTAL JOURNAL, 189 , pp. 212-215.
Bedi R; Gilthorpe MS (2000) Social background of minority ethnic applicants to medicine and dentistry. BRITISH DENTAL JOURNAL, 189 , pp. 152-154.
Bedi R; Lewsey JD; Gilthorpe MS (2000) Changes in oral health over ten years amongst UK children aged 4-5 years living in a deprived multiethnic area. BRITISH DENTAL JOURNAL, 189 , pp. 88-92.
Cunningham SJ; Gilthorpe MS; Hunt NP (2000) Are orthognathic patients different?. EUROPEAN JOURNAL OF ORTHODONTICS, 22 , pp. 195-202.
McGrath C; Bedi R; Gilthorpe MS (2000) Oral health related quality of life - views of the public in the United Kingdom. COMMUNITY DENTAL HEALTH, 17 , pp. 3-7.
McCreadie C; Bennett G; Gilthorpe MS; Houghton G; Tinker A (2000) Elder abuse: do general practitioners know or care?. JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 93 , pp. 67-71.
Lewsey JD; Gilthorpe MS; Bulman J; Bedi R (2000) Is modelling dental caries a 'normal' thing to do?. JOURNAL OF DENTAL RESEARCH, 79 , pp. 159-159.
Gilthorpe MS; Griffiths GS; Zamzuri AT (2000) Are the "burst" and "linear" theories a multilevel phenomenon of the same thing?. JOURNAL OF DENTAL RESEARCH, 79 , pp. 579-579.
Holt RD; Al Lamki S; Bedi R; Dowey JA; Gilthorpe M (1999) Provision of dental general anaesthesia for extractions in child patients at two centres. BRITISH DENTAL JOURNAL, 187 , pp. 498-501.
Jaber MA; Porter SR; Gilthorpe MS; Bedi R; Scully C (1999) Risk factors for oral epithelial dysplasia - the role of smoking and alcohol. ORAL ONCOLOGY, 35 , pp. 151-156.
Jaber MA; Porter SR; Scully C; Gilthorpe MS; Bedi R (1998) The role of alcohol in non-smokers and tobacco in non-drinkers in the aetiology of oral epithelial dysplasia. INTERNATIONAL JOURNAL OF CANCER, 77 , pp. 333-336.
Gilthorpe MS; Lay-Yee R; Wilson RC; Walters S; Griffiths RK; Bedi R (1998) Variations in hospitalization rates for asthma among Black and minority ethnic communities. RESPIRATORY MEDICINE, 92 , pp. 642-648.
Duffy S; Eaton KA; Griffiths GS; Gilthorpe M; Johnson NW (1998) Periodontitis prevalence in adolescents: Partial compared to full mouth recordings.. JOURNAL OF DENTAL RESEARCH, 77 , pp. 922-922.
Gilthorpe MS; Bedi R; Jamjoom M (1998) Social background of ethnic minority applicants to medicine and dentistry. JOURNAL OF DENTAL RESEARCH, 77 , pp. 834-834.
Gilthorpe MS; Bedi R; Alsarheed M (1998) Ethnic variations amongst women choosing medical and dental schools. JOURNAL OF DENTAL RESEARCH, 77 , pp. 834-834.
Darbar UR; Gilthorpe MS; Cleaton-Jones P; Newman HN (1998) Tooth wear and tooth loss in a South African population.. JOURNAL OF DENTAL RESEARCH, 77 , pp. 700-700.
Duffy S; Griffiths GS; Gilthorpe M; Johnson NW; Eaton KA (1998) Periodontitis prevalence and progression in male adolescents over three years.. JOURNAL OF DENTAL RESEARCH, 77 , pp. 864-864.
Bedi R; Gilthorpe MS (1998) Ethnic and gender variations in applicants to medicine and dentistry.. JOURNAL OF DENTAL RESEARCH, 77 , pp. 790-790.
Gilthorpe MS; Bedi R (1997) An exploratory study combining hospital episode statistics with socio-demographic variables, to examine the access and utilisation of hospital oral surgery services.. Community Dent Health, 14 (4), pp. 209-213.
Gilthorpe MS (1997) Application of the Mantel-Haenszel odds ratio in validation of hospital episode statistics data.. Health Serv Manage Res, 10 (2), pp. 79-90.
Wilson RC; Gilthorpe MS; Bedi R (1997) Cost benefits of withdrawing a publicly funded inpatient dental service.. JOURNAL OF DENTAL RESEARCH, 76 , pp. 1032-1032.
Gilthorpe MS; Bedi R (1997) Variations of head injuries by ethnic background.. JOURNAL OF DENTAL RESEARCH, 76 , pp. 948-948.
Gilthorpe MS; Bedi R (1996) Access to inpatient oral surgery services - A socio-economic issue?. JOURNAL OF DENTAL RESEARCH, 75 , pp. 1706-1706.
SORAHAN T; LISTER A; GILTHORPE M; HARRINGTON J (1995) MORTALITY OF COPPER-CADMIUM ALLOY WORKERS WITH SPECIAL REFERENCE TO LUNG-CANCER AND NONMALIGNANT DISEASES OF THE RESPIRATORY SYSTEM, 1946-92. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 52 , pp. 804-812.
Bedi R; Gilthorpe MS (1995) The prevalence of betel-quid and tobacco chewing among the Bangladeshi community resident in a United Kingdom area of multiple deprivation.. Prim Dent Care, 2 (2), pp. 39-42.
BEDI R; GILTHORPE M (1995) THE POTENTIAL USE OF ETHNIC MASS-MEDIA IN HEALTH-EDUCATION. JOURNAL OF DENTAL RESEARCH, 74 , pp. 869-869.
BEDI R; GILTHORPE M; THOMAS D; JONES P (1995) BARRIERS TO DENTAL-CARE FOR ADULTS FROM A MINORITY ETHNIC-BACKGROUND. JOURNAL OF DENTAL RESEARCH, 74 , pp. 869-869.
GILTHORPE M; WILSON R; BEDI R (1995) SOCIOECONOMIC-STATUS AND THE UPTAKE OF INPATIENT DENTAL SERVICES. JOURNAL OF DENTAL RESEARCH, 74 , pp. 436-436.
UPPAL R; BEDI R; GILTHORPE M (1995) THE EVALUATION OF A HEALTH PROMOTION INITIATIVE IN THE WORKPLACE. JOURNAL OF DENTAL RESEARCH, 74 , pp. 498-498.
SORAHAN T; GILTHORPE M (1994) NONDIFFERENTIAL MISCLASSIFICATION OF EXPOSURE ALWAYS LEADS TO AN UNDERESTIMATE OF RISK - AN INCORRECT CONCLUSION. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 51 , pp. 839-840.
BOLDY D; AYRES J; CROCKER J; WATERHOUSE J; GILTHORPE M (1991) INTERPHASE NUCLEOLAR ORGANIZER REGIONS AND SURVIVAL IN SQUAMOUS-CELL CARCINOMA OF THE BRONCHUS - A 10 YEAR FOLLOW-UP-STUDY OF 138 CASES. THORAX, 46 , pp. 871-877.
MOORE P; GILTHORPE M (1991) ANALYSIS OF THE RESONANCE ANGLE OF COSMOS 1603 (1984-106A) NEAR 14-1 RESONANCE. PLANETARY AND SPACE SCIENCE, 39 , pp. 1549-1558.
Morris E; Haward RA; Gilthorpe MS; Craigs C; Forman D The impact of the Calman-Hine report on the processes and outcomes of care for Yorkshire’s breast cancer patients.. Annals of Oncology, .
Teaching Commitments
Module manager and teacher for "Modelling Strategies" for the MSc in Statistical Epidemiology.
Widening Participation
None