AMR Seminar Series: The challenges of AMR surveillance with Dr Jane Freeman and Dr Jessica Mitchell

Tuesday 29 June 2021
11:00am - 12:00pm
Online event
Lectures and seminars
General public

AMR@Leeds is a recently-established, cross-Faculty network and invites you to our on-going seminar series.

In this seminar, Dr Jessica Mitchell, Research Fellow in the Nuffield Centre for International Health and Development, will give an overview to the challenges of AMR surveillance across the One Health sphere. Jess has a background in zoology and animal behaviour, but now works predominantly on the human behaviours driving AMR.

Based on her research in low- and middle-income countries, Jess will discuss how surveillance aims within National AMR guidance documents are not always reflective of a county’s laboratory capacity. AMR surveillance within human health is often prioritised over that of animal and environmental health, and how both these issues can inhibit countries in fully understanding the dynamics of AMR.  

Dr Jane Freeman, Clinical Scientist in Microbiology within Leeds Teaching Hospitals Trust, will then provide a more specific example of AMR surveillance in action by describing the ClosER study: Pan-European, longitudinal surveillance of Clostridioides difficile prevalence and antimicrobial resistance. C. difficile is the leading cause of hospital acquired diarrhoea and has a significant impact upon patients, and the NHS in terms of resource and costs.

The emergence of an epidemic ribotype in the early-mid 2000s led to outbreaks of severe C difficile infections and increased mortality in many countries across the world. This highlighted the need for C. difficile surveillance, to be aware of emerging ribotypes and any associated increase in antimicrobial resistance.

The ClosER study collected isolates from 22 countries across Europe each year for 5 years and is the largest study of C. difficile epidemiology to date. Jane will talk about the results of the study and the picture it built over 5 years of novel emerging ribotypes, rates of resistance and country-specific scenarios. 

If you would like to attend, please respond to Alexandra Pisica