The University has given the seal of approval to the proposed plans to integrate Engineering and Physical Sciences on the north eastern part of campus.
The £96m project was approved by the Council, the University's governing body, earlier this month.
It is set to position the University as a world leading research platform and is the largest, single-project investment ever to have been made on campus.
It is proposed that the new 15,700m2 development will bring together schools in the Faculty of Engineering, with those in Physical Sciences, involving the relocation of the Schools of Computing and Physics and Astronomy.
This will help to foster a culture of inter-disciplinary working in the development of novel materials to address 21st Century challenges.
Areas of research include energy efficient computing, telecommunications, sustainable magnetic materials, sensors for use in biological systems and extreme or remote environments, pharmaceutical formulations, smart foods and medical technologies.
This investment is a substantial part of the Universitys £520m campus development plan and will help to secure our ambition to be one of the UKs top ten research universities.
The facility will include first-class laboratory and specialised teaching spaces, enabling cutting-edge research, and outstanding student experience, whilst enhancing the Universitys research power and strengthening collaboration with industry.
Dennis continued: "The development will provide impetus and academic acceleration in our Engineering and Physical Sciences disciplines.
Its also great news for the Leeds City Region, with the investment further strengthening the Universitys ability to attract major research funding with a consequential impact on the Leeds City Region economy.
Professor Lisa Roberts, Deputy Vice-Chancellor: Research and Innovation, said: The University already has a strong, global reputation for its pioneering science and engineering research, but currently some disciplines that are, and should be, working together are spread across campus."
This investment is about creating a modern, highly flexible space to bring teams and facilities together in a single location to support, stimulate and inspire interdisciplinary approaches to tackling big research questions.
The next stages of the project involve presenting the plans to the Leeds City Council Planning Committee later this year.
Preparatory works have been taking place, including vacating the Estates and Old Mining buildings along with the ancillary buildings such as the Estates workshops.
Estates colleagues have now relocated to a permanent new home in the Facilities Directorate Building, which is located close to Bright Beginnings nursery.
Fine Art, History of Art and Cultural Studies have moved from the Old Mining building to the former School of Geography; which has been transformed to create the new Fine Art, History of Art and Cultural Studies Building, following a £7.6m investment.
The site is expected to be vacant next month following the final move, when the Estates workshops are relocated to the Generating Station Complex.
Following this, a site survey will be conducted with a view to tendering the demolition works contract ahead of a start on site in early 2017. Full project completion is scheduled for 2020.
This news follows last months announcement marking Leeds City Councils approval of Nexus - a £40m innovation and enterprise centre, set to open in 2018.
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